Chai Discovery Lands $70M for Generative Antibody Design

According to Chai Discovery’s co-founders, a biotech firm spent over three years and $5 million trying to generate an antibody for a difficult molecular target. The search involved traditional wet-lab screening and failed to yield results. This year, Chai Discovery claims it solved the same problem in just two weeks using Chai-2, a Gen AI model capable of designing antibodies from scratch with a reported experimental hit rate exceeding 15%. Founded in 2024, Chai Discovery is developing AI foundation models that simulate and reprogram the interactions between biochemical molecules: an effort aimed at transforming biology into a deterministic design process. The company has now raised $70 million in Series A funding led by Menlo Ventures and its Anthology Fund, a joint initiative with A