In early 2025, Tahoe Therapeutics released Tahoe-100M, a dataset of more than 100 million data points detailing how cancer cells respond to over 1,000 molecules. Within months, it had been downloaded nearly 100,000 times by AI labs and research institutions. The nonprofit Arc Institute used it to build an open-source virtual cell model that doubled the predictive accuracy of earlier systems. For the San Francisco-based startup, it was validation for their goals: digitally replicating the complexity of living cells to improve the odds of developing effective drugs.
Tahoe was founded in 2022 by chief executive Nima Alidoust, chief scientific officer Johnny Yu, and established University of California scientists Hani Goodarzi and Kevan Shokat. All four have backgrounds spanning single-cell
$30M Round Fuels Tahoe Therapeutics’ Virtual Cell Model Ambitions
- By Mukundan Sivaraj
- Published on
The company plans to expand from 100 million to one billion single-cell datapoints
