Cleveland Clinic Partners With Luminai to Transform Health System Operations

Cleveland Clinic is partnering with Luminai to automate complex administrative workflows, starting with the processing of faxed patient referrals.
Cleveland Clinic has partnered with Luminai, an AI-native enterprise automation platform for healthcare operations, to co-develop and deploy AI automation across complex administrative workflows.
The collaboration will initially focus on external referrals, many of which still arrive by fax and require staff to sort, prioritize and transcribe information into the electronic medical record (EMR). Luminai’s system is designed to identify incoming referral documents, interpret their clinical context, match them with the appropriate patient and order type, and transcribe the information into the EMR for follow-up. Cleveland Clinic’s referral process continues to include fax submission for some physician referrals.
The deployment builds on Cleveland Clinic’s use of Luminai for referral automation, extending the application of AI to a broader set of operational workflows. The earlier Cleveland Clinic-Luminai referral automation effort focused on reducing manual work involved in processing incoming referrals.
AI Targets Complex Administrative Workflows
Cleveland Clinic said the partnership will address processes that involve unstructured data, multiple hand-offs and complex decision-making. The health system plans to use the initial deployment to identify lessons that could inform automation of similar workflows elsewhere in the organization.
“Automation only delivers value when it reflects the realities of clinical and operational work,” Rohit Chandra, Chief Digital Officer at Cleveland Clinic, said. He added that the collaboration was intended to reduce administrative burden while improving patient satisfaction.
The referral workflow illustrates one of the challenges health systems face when administrative information arrives outside structured digital systems. Luminai said its platform combines healthcare-trained AI models with a configurable workflow engine and human-in-the-loop validation, allowing organizations to adapt workflows to their own operating requirements.
Other health systems have also begun applying AI to administrative processes beyond clinical care, including referrals and operational workflows. Summa Health’s use of AI for referrals and other operations provides another example of health systems applying automation to work that traditionally requires staff to move information between systems.
Luminai Engineers to Work With Cleveland Clinic Teams
As part of the partnership, Luminai’s forward-deployed engineering team will work alongside Cleveland Clinic’s clinical and operational staff to adapt the automation workflows. The companies said this approach is intended to reduce the time between deployment and measurable operational impact.
The broader objective is to apply the same approach to other administrative functions with similar characteristics. Cleveland Clinic and Luminai said the initial referral deployment could provide a basis for addressing workflows involving high volumes of unstructured documentation, manual hand-offs and time-sensitive decisions.
“Healthcare organizations have an opportunity to use AI to modernize and transform operations while still relying on their existing systems of record,” Kesava Kirupa Dinakaran, Founder and CEO of Luminai, said.
Luminai is headquartered in San Francisco and has raised $60 million to date, according to the company. Its investors include General Catalyst, Peak XV Partners, Define Ventures, Y Combinator, Moxxie Ventures and Craft Ventures.
Cleveland Clinic is a nonprofit academic medical center with 83,000 employees worldwide, including more than 6,600 salaried physicians and researchers and 21,900 registered nurses and advanced practice providers. In 2025, its health system recorded 15.9 million outpatient encounters, 343,000 hospital admissions and observations, and 336,000 surgeries and procedures.
The partnership comes as healthcare organizations increasingly look to AI for operational efficiency and staff capacity. AI’s potential to increase patient capacity has emerged as one rationale for applying automation to administrative work alongside clinical applications.
Key Takeaways
- Cleveland Clinic partners with Luminai to automate administrative workflows using AI technology.
- Initial focus on automating processing of faxed patient referrals to improve efficiency.
- Luminai’s system interprets clinical context and integrates referral information into electronic medical records.
- Collaboration builds on previous referral automation efforts to enhance operational workflows.
- Aim to reduce manual processing time and improve patient referral management.